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 differ. I daresay this is
chiefly due to muddy-headedness on my part, but I do not think wholly
so. Your many terms, not defined, "developed germs," "fertile," and
"sterile germs" (the word "germ" itself from association misleading to
me) "stirp," "sept," "residue," etc., etc., quite confounded me. If I
ask myself how you derive, and where you place the innumerable gemmules
contained within the spermatozoa formed by a male animal during its
whole life, I cannot answer myself. Unless you can make several parts
clearer I believe (though I hope I am altogether wrong) that only a few
will endeavour or succeed in fathoming your meaning. I have marked a
few passages with numbers, and here make a few remarks and express my
opinion, as you desire it, not that I suppose it will be of any use to
you.

1. If this implies that many parts are not modified by use and disuse
during the life of the individual, I differ widely from you, as every
year I come to attribute more and more to such agency. (271/2. This
seems to refer to page 329 of Mr. Galton's paper. The passage must have
been hastily read, and has been quite misunderstood. Mr. Galton has
never expressed the view attributed to him.)

2. This seems rather bold, as sexuality has not been detected in some
of the lowest forms, though I daresay it may hereafter be. (271/3. Mr.
Galton, op. cit., pages 332-3: "There are not of a necessity two
sexes, because swarms of creatures of the simplest organisations mainly
multiply by some process of self-division.")

3. If gemmules (to use my own term) were often deficient in buds, I
cannot but think that bud-variations would be commoner than they are in
a state of nature; nor does it seem that bud-variations often exhibit
deficiencies which might be accounted for by the absence of the proper
gemmules. I take a very different view of the meaning or cause of
sexuality. (271/4. Mr. Galton's idea is that in a bud or other
asexually produced part, the germs (i.e. gemmules) may not be completely
representative of the whole organism, and if reproduction is continued
asexually "at each successive stage there is always a chance of some one
or more of the various species of germs... dying out" (page 333). Mr.
Galton supposes, in sexual reproduction, where two parents contribute
germs to the embryo the chance of deficiency of any of the necessary
germs is greatly diminished. Darwin's "very different view of the
meaning or cause of sexuality" is no doubt that given in "Cross and
Self Fertilisation"--i.e., that sexuality is equivalent to changed
conditions, that the parents are not representative of different sexes,
but of different conditions of life.)

4. I have ordered "Fraser's Magazine" (271/5. "The History of Twins,"
by F. Galton, "Fraser's Magazine," November, 1875, republished with
additions in the "Journal of the Anthropological Institute," 1875. Mr.
Galton explains the striking dissimilarity of twins which is sometimes
met with by supposing that the offspring in this case divide the
available gemmules between them in such a way that each is the
complement of the other. Thus, to put the case in an exaggerated way,
similar twins would each have half the gemmules A, B, C,...Z., etc,
whereas, in the case of dissimilar twins, one would have all the
gemmules A, B, C, D,...M, and the other would have N...Z.), and am
curious to learn how twins from a single ovum are distinguished from
twins from two ova. Nothing seems to me more curious than the similarity
and dissimilarity of twins.

5. Awfully difficult to understand.

6. I have given almost the same notion.

7. I hope that all this will be altered. I have received new and
additional cases, so that I have now not a shadow of doubt.

8. Such cases can hardly be spoken of as very rare, as you would say if
you had received half the number of cases I have.

(271/6. We are unable to determine to what paragraphs 5, 6, 7, 8 refer.)

I am very sorry to differ so much from you, but I have thought that you
would desire my open opinion. Frank is away, otherwise he should have
copied my scrawl.

I have got a good stock of pods of sweet peas, but the autumn has been
frightfully bad; perhaps we may still get a few more to ripen.

LETTER 272. TO T.H. HUXLEY. Down, November 12th [1875].

Many thanks for your "Biology," which I have read. (272/1. "A Course of
Practical Instruction in Elementary Biology," by T.H. Huxley and H.N.
Martin, 1875. For an account of the book see "Life and Letters of T.H.
Huxley," Volume I., page 380.) It was a real stroke of genius to think
of such a plan. Lord, how I wish I had gone through such a course!

LETTER 273. TO FRANCIS GALTON. December 18th [1875].

George has been explaining our differences. I have admitted in the
new edition (273/1. In the second edition (1875) of the "Variation of
Animals and Plants," Volume II., page 350, reference is made to Mr.
Galton's transfusion experiments, "Proc. R. Soc." XIX., page 393; also
to Mr. Galton's letter to "Nature," April 27th, 1871, page 502. This
is a curious mistake; the letter in "Nature," April 27th, 1871, is by
Darwin himself, and refers chiefly to the question whether gemmules may
be supposed to be in the blood. Mr. Galton's letter is in "Nature,"
May 4th, 1871, Volume IV., page 5. See Letter 235.) (before seeing
your essay) that perhaps the gemmules are largely multiplied in the
reproductive organs; but this does not make me doubt that each unit of
the whole system also sends forth its gemmules. You will no doubt have
thought of the following objection to your views, and I should like to
hear what your answer is. If two plants are crossed, it often, or rather
generally, happens that every part of stem, leaf, even to the hairs,
and flowers of the hybrid are intermediate in character; and this hybrid
will produce by buds millions on millions of other buds all exactly
reproducing the intermediate character. I cannot doubt that every unit
of the hybrid is hybridised and sends forth hybridised gemmules. Here we
have nothing to do with the reproductive organs. There can hardly be a
doubt from what we know that the same thing would occur with all those
animals which are capable of budding, and some of these (as the compound
Ascidians) are sufficiently complex and highly organised.

LETTER 274. TO LAWSON TAIT. March 25th, 1876.

(274/1. The reference is to the theory put forward in the first edition
of "Variation of Animals and Plants," II., page 15, that the asserted
tendency to regeneration after the amputation of supernumerary digits
in man is a return to the recuperative powers characteristic of a "lowly
organised progenitor provided with more than five digits." Darwin's
recantation is at Volume I., page 459 of the second edition.)

Since reading your first article (274/2. Lawson Tait wrote two notices
on "The Variation of Animals and Plants under Domestication" in the
"Spectator" of March 4th, 1876, page 312, and March 25th, page 406.),
Dr. Rudinger has written to me and sent me an

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